The Gunners are 12 points behind league leaders Liverpool and can reduce the deficit before the Reds face Everton tomorrow.
Formation: 4-3-3
Predicted Line-up:
David Raya has played every minute in the top-flight this campaign, keeping 11 clean sheets. He will be eyeing another shut-out tonight.
The backline could stay unchanged. Jurrien Timber and Myles Lewis-Skelly are expected to continue in the right and left-back positions.
William Saliba and Gabriel Magalhaes will start in central defence.
The midfield could stay unchanged too. Thomas Partey looks poised to feature as the holding midfielder ahead of Jorginho again.
Martin Odegaard and Declan Rice are expected to start in central midfield.
There could be one change in the final third. Leandro Trossard is likely to be dropped. Gabriel Martinelli should start on the left wing.
Bukayo Saka could make his long-awaited return from injury on the right wing. Mikel Merino should lead the attack against the Cottagers.
Predicted Arsenal line-up (4-3-3) vs Fulham: Raya; Timber, Saliba, Gabriel, Lewis-Skelly; Partey, Rice, Odegaard; Saka, Merino, Martinelli.